The obesity paradox in chronic disease: facts and numbers

In the investigation of Whether this is justified depends upon the state of health and should be judged individually. For patients with established chronic disease, there is sufficient evidence to support the benefits of large body size, i.e., the obesity paradox, found that the uniform finding is shared over a variety of cardiovascular, pulmonary, and renal diseases and is counterintuitive to the current concepts on ideal body weight. The scientific community has to increase the awareness about differences for optimal body size in health and disease. Simultaneously, clinicians have to be aware about body weight dynamics implications and should interpret the changes in the context of an underlying disease in order to implement the best available management.(1)

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(1) "The obesity paradox in chronic disease: facts and numbers" by Lainscak M, von Haehling S, Doehner W, Anker SD.